3.0T磁敏感加权成像在检测腔隙性脑梗塞中微出血的应用

目的应用磁敏感加权(SWI)技术检测腔隙性脑梗塞患者中脑微出血(CMBs)病变,评估SWI序列在检测腔隙性脑梗塞患者微出血的价值。材料与方法收集50例腔隙性梗塞患者,同时收集同期50例健康成人作为对照组,共100例。两组均行颅脑常规磁共振(包括T2WI、T2FLAIR、T1FLAIR)及SWI检查。图像评价:对常规序列及SWI显示CMBs的例数、部位、数量及阳性率进行统计学分析,对SWI及常规序列上腔隙性梗塞灶数目与微出血灶严重程度进行Spearman秩相关分析。结果 24例腔隙性梗塞在SWI序列清楚显示CMBs病灶,仅3病例在T1WI序列显示,5病例在T2WI上显示,SWI、常规T2WI及T1WI序列比较有统计学意义(P0.05)。在SWI序列中,对照组、腔隙性梗塞组的微出血阳性率及微出血灶数目均有统计学意义(P0.01);在腔隙性梗塞组中,腔隙性梗塞数目与微出血灶的严重程度呈正相关。结论 SWI序列显示腔隙性梗塞患中微出血灶优于常规序列,对腔隙性梗塞患者怀疑脑内有微出血时,SWI序列应作为首选检查方法。

Application of Susceptibility Weighted Imaging Detecting Cerebrai Microbleeds in Patients with Lacunar Infarction Disease

Objective To evaluate the value of detecting cerebral microbleeds in patients with lacunar infarction by susceptibility weighted imaging（SWI） and conventional FSE sequences.Materials and Methods The study sample consisted of 50 patients and 50 cases healthy population, were examined using SWI and conventional FSE sequences by GE 3.0 T MR machine with 32 tunnel HR head coil. The number, frequency and locations of CMBs were analyzed by SWI and FSE. The value of SWI and FSE sequences in founding CMBs were compared. The number of CMBs in patients with lacunar infarction and the number of lacunar infarction. were analyzed.Results 24 cases patients with CMBs on SWI were founded in 50 cases patients with lacunar infarction, 5 cases patients on T2WI were founded in 24 cases patients with CMBs on SWI, only 3 cases patients on T1WI were founded. On SWI sequences, compared with the controls subjects and patients with CMBs of lacunar infarction had significant increased positive rate and numbers of CMBs （P〈0.01）. There was a correlation between the number of CMBs in patients with lacunar infarction and the number of lacunar infarction.Conclusion SWI sequence was much better than FSE, SWI sequence is more sensitive than FSE in detecting CMBs and should be as the first choice.