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妊娠晚期妇女凝血及纤溶系统的改变与临床意义
引用本文:杨蓬勃. 妊娠晚期妇女凝血及纤溶系统的改变与临床意义[J]. 军事医学科学院院刊, 2007, 31(2): 155-156
作者姓名:杨蓬勃
作者单位:卫生部北京医院检验科,100730
摘    要:目的:探讨妊娠晚期妇女凝血及纤溶系统的改变与临床意义.方法:选取180例妊娠晚期(平均孕周37.5周)妇女,检测其血浆中凝血酶原时间(PT),活化全血凝固时间(APTT),纤维蛋白(FIB),D-二聚体(D-Dimer)等4项指标.选取健康非妊娠妇女45例作为对照.结果:妊娠晚期妇女血浆PT,AFTT,FIB,D-Dimer值与对照组比较差异均有统计学意义(P<0.05).结论:妊娠晚期妇女血液处于高凝状态,检测上述4项指标,对防止妊娠晚期血栓形成、妊娠高血压综合征等并发症有一定临床意义.

关 键 词:妊娠晚期  凝血及纤溶系统  血栓形成  妊娠并发症  妊娠晚期  非妊娠妇女  凝血酶原时间  纤溶系统  临床  统计学意义  clinical significance  pregnant women  terminal  system  coagulation  并发症  妊娠高血压综合征  血栓形成  高凝状态  血液  比较差异  对照组  结果  健康
文章编号:1000-5501(2007)02-0155-02
修稿时间:2006-08-22

The changes in coagulation and fibrinolytic system in terminal pregnant women and their clinical significance
YANG Peng-Bo. The changes in coagulation and fibrinolytic system in terminal pregnant women and their clinical significance[J]. Bulletin of the Academy of Military Medical Sciences, 2007, 31(2): 155-156
Authors:YANG Peng-Bo
Affiliation:Department of Laboratory Medicine, Beijing Hospital, Beijing 100730, China
Abstract:Objective: To evaluate changes in coagulation and fibrinolytic system in terminal pregnant women and their clinical significance. Methods: The concentrations of PT,APTT,FIB,and D-Dimer in 180 terminal pregnant women and 45 nonpregnant women were determined. Results:PT and APTT shortened in terminal pregnant women, with significant difference between terminal pregnant women and nonpregnant women(P<0.05). The values of FIB and D-Dimer were higher in pregnant women,with significant difference between nonpregnant women and terminal pregnant women(P<0.05) .Conclusion: Pregnant women are in hypercoagulable state. The coagulation and fibrinolytic system can be applied to monitor thrombosis in pregnant women.
Keywords:terminal pregnancy  coagulation and fibrinolytic system  thrombosis  pregnancy complications
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