|
|||||
|
|
Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection |
|
| Authors: | S. Nagafuchi H. Ishibashi K. Anzai K. Ohshima Y. Ohno N. Fukushima M. Hashizume K. Sugimachi H. Chuman M. Kikuchi Y. Niho |
| Affiliation: | (1) First Department of Internal Medicine, Faculty of Medicine, Kyushu University, 812 Fukuoka, Japan;(2) Department of Pathology, School of Medicine, Fukuoka University, 814 Fukuoka, Japan;(3) Second Department of Surgery, Faculty of Medicine, Kyushu University, 812 Fukuoka, Japan;(4) Department of Orthopedics, Faculty of Medicine, Kyushu University, 812 Fukuoka, Japan |
| Abstract: | A 42-year-old Japanese man with chronic active Epstein-Barr virus (EBV) infection initially responded to treatment with interleukin-2 (IL-2). Six months later he developed thrombosis in the hepatic veins, and Budd-Chiari syndrome associated with severe hepatic damage was diagnosed. He also developed a solitary EBV-positive plasmacytoma in the right femur. Since these rare complications occurred after long-term IL-2 therapy, the possibility that long-term IL-2 therapy might cause Budd-Chiari syndrome and liver damage as well as EBV-associated plasmacytoma is discussed.Abbreviations EBV Epstein-Barr virus - EBER1 EpsteinBarr virus-encoded RNA-1 - IL-2 interleukin-2 - NK natural killer - LMP latent membrane protein - LAK lymphokine activated killer |
| Keywords: | Epstein-Barr virus Epstein-Barr virus encoded RNA-1 Budd-Chiari syndrome Plasmacytoma Interleukin 2 |
| 本文献已被 SpringerLink 等数据库收录！ | |