Deep cerebral venous sinus thrombosis often presents with neuropsychologic symptoms. |
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| Authors: | M von Mering M Stiefel K Brockmann R Nau |
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| Institution: | 1. Section of Thoracic Surgery, Yale School of Medicine, New Haven, Connecticut;2. Yale School of Public Health, New Haven, Connecticut;3. Division of Thoracic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California;1. Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA;2. Department of Sociology, University of Alabama at Birmingham, Birmingham, AL, USA;3. UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA;4. Birmingham VA Medical Center, Birmingham, AL, USA;5. Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH, USA;6. Department of Neurology, Brigham and Women''s Hospital, Boston, MA, USA |
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| Abstract: | The outcome of cerebral venous sinus thrombosis (CVST) depends on rapid diagnosis and initiation of effective anticoagulation. We report seven cases of a subgroup with deep cerebral venous sinus thrombosis (DCVST) treated in our institution since 1990. Six of our seven patients presented with early neuropsychological deficits (mental obtundation, bradyphrenia or apathia). This clinical presentation, in combination with headache, and focal neurological deficits, aids the early diagnosis of DCVST. Thalamic hyperintensities on T2-weighted MRI images, previously considered infarctions, were fully reversible during treatment with heparin. This indicates that early in the course of the disease they correspond to vasogenic oedema. |
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