免疫增强型肠内营养制剂对老年胃癌术后化疗免疫功能的影响分析

目的观察免疫增强型肠内营养制剂对老年胃癌患者术后免疫功能以及营养状态的影响，为此类患者的有效治疗方法提供参考。 方法选择2014年1月至2015年2月胃癌手术后进行化疗的80例患者，按照随机数表法分为对照组（采用常规的肠内营养制剂）和观察组（采用免疫增强型肠内营养制剂），各40例。比较两组患者的免疫球蛋白、T细胞亚群、化疗之后营养指标以及住院天数、排便时间以及首次排气时间。 结果治疗后观察组患者的IgM、IgG、IgA上升幅度显著优于对照组，CD3、CD4、CD8明显优于对照组，TF、PA、ALB、Hb均高于对照组，差异有统计学意义（P<0.05）；观察组患者住院天数、排便时间以及首次排气时间明显短于对照组，差异有统计学意义（P<0.05）。 结论胃癌术后化疗通过免疫增强型肠内营养制剂能够显著改善免疫功能，缩短患者的住院时间，值得在临床上推广。

Effect analysis of postoperative immune-enhancing enteral nutrition on immune function in elderly patients with gastric chemotherapy

ObjectiveTo observe the effect of postoperative immune-enhancing enteral nutrition on elderly gastric cancer patients. MethodsEighty patients undergoing chemotherapy after stomach cancer surgery were chosen from January 2014 to February 2015. According to the random number table method, patients were divided into control group and observation group, with 40 patients in each group. The observation group were treated with immune-enhancing enteral nutrition, while the control group with conventional enteral nutrition. Immunoglobulin, T cell subsets, nutrition indicators after chemotherapy, hospital stay defecation, and the first exhaustion time in two groups were compared. ResultsAfter treatment, compared to the control group, in the observation group IgM, IgG, IgA increased significantly, CD3, CD4, CD8, TF, PA, ALB, Hb were higher (P<0.05), hospital stay time, defecation time and the first exhaustion time were significantly shorter, and these differences were statistically significant (P<0.05). ConclusionPostoperative chemotherapy in gastric cancer patients can significantly improve the immune function, and shorten the length of hospital stay, which is worthy of clinical promotion.