合并睡眠呼吸暂停的中青年脑梗死患者颈动脉粥样硬化的研究

目的 探讨合并睡眠呼吸暂停（sleep apnea-hypopnea，SA）的中青年脑梗死（cerebral infarction，CI）患者颈动 脉粥样硬化（carotid atherosclerosis，CAS）情况。方法 80 例中青年脑梗死患者分为单纯 CI 组（40 例）、CI 合并 SA 组（40 例），两组患者均行颈动脉彩色多普勒超声检查，记录颈动脉内中膜厚度（intima-media thickness，IMT）及斑 块情况。结果 中青年 CI 合并 SA 组及单纯 CI 组患者颈动脉 IMT 分别为 (1.335±0.219)mm、(1.088±0.202)mm，CI 合 并 SA 组高于单纯 CI 组（P<0.01）,CI 合并 SA 组及单纯 CI 组患者斑块发生率分别为 75%、25%，CI 合并 SA 组高于单 纯 CI 组（P<0.01），CI 合并 SA 组及单纯 CI 组患者不稳定斑块发生率分别为 71%、30%，CI 合并 SA 组高于单纯 CI 组 （P<0.05）。结论 中青年 CI 合并 SA 患者颈动脉粥样硬化程度更重。

Study of carotid atherosclerosis in middle-aged and young patients of cerebral infarction with sleep apnea-hypopnea

Objective To investigate the carotid atherosclerosis(CAS)in middle-aged and young patients of cerebral infarction (CI) with sleep apnea-hypopnea (SA). Methods 80 middle-aged and young patients of CI were divided into two groups, only CI group (40 cases)) and CI combined with SA group (cases 40).All patients were checked carotid artery through color doppler ultrasound and record intima-media thickness(IMT) and the state of plaques. Results The IMT of middle-aged and young patients in CI combined with SA group and in only CI group were (1.335±0.219)mm,(1.088±0.202)mm respectively, the degree of IMT in CI combined with SA group was significantly higher than that in only CI group (P<0.01).The rate of plaque occurrence in CI combined with SA group and in only CI group were 75%,25% respectively, the rate of plaque occurrence in CI combined with SA group was significantly higher than that in only CI group (P<0.01).The rate of unstable plaque occurrence in CI combined with SA group and in only CI group were 71%,30% respectively, the rate of unstable plaque occurrence in CI with SA group was significantly higher than that in only CI group (P<0.05). Conclusion There is higher degree of carotid artery atherosclerosis in the middle-aged and young patients of CI combined with SA group than that of only CI group.