纯钛在仿真蛋白环境中腐蚀性能的电化学阻抗谱分析

目的 在高仿真环境中,采用电化学阻抗法分析纯钛种植材料的腐蚀性能。方法 以PBS液为对照组,细胞培养液为实验组,采用电化学分析仪测试钛在含血清蛋白体系中的电化学阻抗谱,利用EIS-Nyquist图、EIS-Bode图及等效电路的拟合分析,研究血清蛋白对钛的抗腐蚀性能的影响,采用SPSS11.0软件包对数据进行统计学分析。结果 纯钛材料在细胞培养液中的氧化膜阻抗值（24.8±3.9）×10⁵ Ω显著大于在PBS液中的阻抗值（6.7±0.8）×10⁵ Ω（P<0.05）。纯钛在PBS中低频区的相位角约为55°,而在细胞培养液中低频区的相位角约为75°。结论 机体环境中的血清蛋白能够影响钛金属在体液中的腐蚀性能。

Electrochemical impedance spectroscopic study of titanium in physiological environment with blood-serum protein

PURPOSE: Electrochemical impedance spectroscopy (EIS) was employed to study the corrosion behaviour of titanium in dummy environment with blood-serum protein. METHODS: EIS of titanium in PBS and cell culture fluid was acquired by advanced electrochemical system. The characteristic of EIS-Nyquist and EIS-Bode were investigated and the equivalent circuit was used to analyze the EIS results. The data was analyzed using SPSS 11.0 software package. RESULTS: The corrosion resistance of the titanium in cell culture fluid was significantly higher than that in PBS (P<0.05). The phase angle of TiO₂-based passive film at low frequency decreased to 55° when titanium was in PBS, but 75° when in cell culture fluid. CONCLUSIONS: The blood-serum protein plays an important role in the corrosion behaviour of titanium in physiological environment.