| 胎儿单脐动脉的研究进展 |
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| 引用本文： | 邓春艳,王晓东,余海燕. 胎儿单脐动脉的研究进展[J]. 中华妇幼临床医学杂志(电子版), 2015, 11(6): 786-788. DOI: 10.3877/cma.j.issn.1673-5250.2015.06.022 |
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| 作者姓名： | 邓春艳 王晓东 余海燕 |
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| 作者单位： | 1. 610041 成都，四川大学华西第二医院妇产科 |
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| 摘 要： | 正常胎儿的脐带有2条脐动脉，而单脐动脉(SUA)胎儿的脐带中仅为1条脐动脉，系脐带发育及结构异常。SUA的诊断主要依靠产前超声检查和产后胎盘、脐带大体检查及其病理学检查。目前，SUA的发生机制尚未阐明。越来越多的研究结果显示，SUA是胎儿先天畸形、染色体核型异常、早产及低出生体质量的软标记，SUA亦可能引起胎儿宫内生长受限及出生后生长发育不良等不良结局。笔者拟就SUA的概念及分类、诊断、发生机制、与之相关的胎儿畸形和染色体核型异常等综述如下。
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| 关 键 词： | 单脐动脉 诊断 先天畸形 染色体畸变 胎儿 |
| 收稿时间： | 2015-02-08 |
Research progress of fetal single umbilical artery |
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| Chunyan Deng,Xiaodong Wang,Haiyan Yu. Research progress of fetal single umbilical artery[J]. Chinese JOurnal of Obstetrics & Gynecology and Pediatrics, 2015, 11(6): 786-788. DOI: 10.3877/cma.j.issn.1673-5250.2015.06.022 |
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| Authors: | Chunyan Deng Xiaodong Wang Haiyan Yu |
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| Affiliation: | 1. Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China |
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| Abstract: | Normal umbilical cord have two umbilical artery, however, only one in the single umbilical artery (SUA) fetus. The diagnose of SUA relies mainly on ultrasound, the gross examination and pathological examination for placenta and umbilical cord after labor.Currently, the cause and mechanism of SUA are still unclear. More and more literatures indicate that SUA is a soft maker for fetal malformation, chromosome abnormality, preterm labor and low weight. SUA may lead to some bad outcomes, such as intrauterine growth restriction and retarded growth. This review focuses on the diagnosis, mechanism, relative fetal malformations and chromosome abnomality of SUA. |
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| Keywords: | Single umbilical artery Diagnosis Congenital abnormalities Chromosome aberrations Fetus |
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