地中海贫血与红细胞直方图和血小板直方图相关性

目的探讨地中海贫血病人与非地中海贫血病人血细胞检验报告中红细胞直方图和血小板直方图等指标的相关性。方法统计2005年1月~2012年12月期间我院门诊住院病人全自动血细胞分析仪的血细胞检验报告且均有地中海贫血基因检测结果共200例，结合地中海贫血基因检测结果，分为二组，一组为确诊的地中海贫血100例病人血细胞检验报告，另一组为地中海贫血基因检测正常的非地中海贫血100例病人血细胞检验报告，对两组病人血细胞检验结果的红细胞直方图图形和血小板直方图图形进行比对。结果地中海贫血病人血细胞检验结果的血小板的直方图呈现明显的双峰特征82例；血小板的直方图没有双峰特征的18例；红细胞直方图单峰明显左移79例，没有左移的21例。基因检测正常的非地中海贫血病人血细胞检验报告血小板的直方图呈现明显的双峰特征8例；血小板的直方图没有双峰特征的92例；红细胞直方图单峰明显左移10例，没有左移的90例。两组对照结果比较差异有统计学意义（P < 0.05）。结论从血细胞检验报告单中观察血小板的直方图及红细胞直方图的形态特征, 通过血细胞常规检验结果可对地中海贫血的快速筛查提供较可靠的临床诊断依据。结果地中海贫血病人血细胞检验结果的血小板的直方图呈现明显的双峰特征82例；血小板的直方图没有双峰特征的18例；红细胞直方图单峰明显左移79例，没有左移的21例。基因检测正常的非地中海贫血病人血细胞检验报告血小板的直方图呈现明显的双峰特征8例；血小板的直方图没有双峰特征的92例；红细胞直方图单峰明显左移10例，没有左移的90例。两组对照结果比较差异有统计学意义（P < 0.05）。结论从血细胞检验报告单中观察血小板的直方图及红细胞直方图的形态特征, 通过血细胞常规检验结果可对地中海贫血的快速筛查提供较可靠的临床诊断依据。

The mediterranean anemia and RBC histogram and platelet histogram correlation

ObjectiveTo discuss the Mediterranean anemia patients and the Mediterranean anemia patients blood test report in RBC histogram and indexes of blood platelet histogram correlation.MethodsStatistics in January 2005 to December 2012 our hospital outpatient hospital patients fully automatic blood cell analyzer blood test report all test results of 200 cases with Mediterranean anemia gene, Combined with Mediterranean anemia gene test results, Divided into two groups, A group for the diagnosis of the Mediterranean anemia blood test report 100 cases of patients, Another group of Mediterranean anemia gene detects the Mediterranean anemia in 100 cases of normal patients blood test report, Blood test results of two groups of patients of red blood cell and platelet histogram graph compares histogram graphics.ResultsThe Mediterranean anemia patients blood test results of platelet histogram presents obvious bimodal characteristics of 82 cases; Platelet histogram of bimodal characteristics of 18 cases; Red blood cells obviously single-peak histograms left 79 cases, No shift to the left of the 21 cases. Gene detects the normal of the Mediterranean anemia patients blood test report platelet histogram shows the bimodal characteristics of 8 cases of obvious; Platelet histogram of bimodal characteristics of 92 cases; 10 cases of RBC histogram unimodal apparent shift to the left, 90 cases without a shift to the left. The comparison results compare similar between the two groups was statistically significant (P < 0.05).ConclusionsFrom the blood test report of observing platelet histogram and histogram of red blood cells morphological characteristics. Through the blood routine test results can provide a rapid screening of Mediterranean anemia and reliable clinical diagnosis basis.