反常性痤疮17例临床分析

【摘要】 目的 探讨反常性痤疮患者的临床特点以及治疗方案。 方法 对门诊诊治的17例反常性痤疮患者的一般情况、临床特点、治疗方案进行回顾性分析。 结果 17例患者均为男性，发病年龄20岁左右，病程2 ~ 50年，主要临床表现为颈部、腋窝、腹股沟、会阴、臀部出现疼痛性炎性丘疹、结节、脓肿，伴瘘管窦道形成，反复发作。10例患者有家族史，7例为散发病例。治疗方法主要是口服维A酸类药物联合抗生素治疗，较严重的患者采用外科手术治疗。 结论 反常性痤疮患者以顶泌汗腺部位出现脓肿、窦道、瘢痕为主要临床表现，治疗应根据皮损的严重程度选择不同的治疗方案。

Clinical analysis of 17 cases of acne inversa

Hui Yun*, Li Hailing, Li Zhiliang, Xu Haoxiang, Li Chengrang, Zhang Guoyi, Wang Baoxi. *Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, ChinaCorresponding author: Wang Baoxi, Email: wangbx@ncstdlc.org 【Abstract】 Objective To analyze the clinical characteristics and treatment of acne inversa. Methods Seventeen outpatients with acne inversa were collected in the Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College from January 1, 2012 to December 31, 2012. The general condition, clinical feature and treatment of these patients were retrospectively analyzed. Results All the patients were male with the age at onset being about 20 years and disease duration varying from 2 to 50 years. Characteristic clinical manifestations were recurrent tender inflammatory papules, nodules, abscesses, fistulae and sinus tracts in the neck, axillary fossa, groin, perineum and buttocks. Among these patients, 10 had a family history and seven were sporadic with mild symptoms. Oral tretinoin combined with antibiotics were the main treatment, and surgical treatment was usually used for severe patients. Conclusions Acne inversa is mainly manifested as abscess, sinus and scars in areas bearing apocrine sweat glands, and therapeutic regimen should be selected according to the severity of lesions.