| 肺癌患者血清一氧化氮与癌胚抗原测定研究 |
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| 引用本文： | 施根林,何海明,刘金波,王新元. 肺癌患者血清一氧化氮与癌胚抗原测定研究[J]. 实用临床医学(江西), 2002, 3(4): 9-10 |
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| 作者姓名： | 施根林 何海明 刘金波 王新元 |
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| 作者单位： | 武警江苏总队医院检验科 江苏扬州225003(施根林，何海明，刘金波)，武警江苏总队医院检验科 江苏扬州225003(王新元) |
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| 摘 要： | 目的 :了解肺癌患者血清一氧化氮 (NO)含量变化 ,以及与癌胚抗原 (CEA)的关系。方法 :用改进Griess法及放射免疫法测定了 17例肺癌患者及 2 9例正常对照组血清NO与CEA含量。结果 :肺癌患者血清NO含量明显高于对照组 (P <0 .0 1) ,血清NO与CEA阳性率分别为 94 .12 %和 6 4 .71% (P <0 .0 5 )。血清NO与CEA含量之间呈正相关 (γ =0 .815 ,P <0 .0 1)。结论 :血清NO含量测定对肺癌的诊断具有重要参考价值
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| 关 键 词： | 肺癌 血清 一氧化氮 癌胚抗原 测定 |
| 文章编号： | 1009-8194(2002)04-0009-02 |
Determination of Serum Nitric Oxide and Carcinoembryonic Antigen in Patients with Lung Cancer and its Clinical Significance |
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| Shi Gen lin,He Hai ming,Liu Jin bo,Wang Xin yuan. Determination of Serum Nitric Oxide and Carcinoembryonic Antigen in Patients with Lung Cancer and its Clinical Significance[J]. Practical Clinical Medicine, 2002, 3(4): 9-10 |
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| Authors: | Shi Gen lin He Hai ming Liu Jin bo Wang Xin yuan |
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| Abstract: | Objective: To investigate the changes of serum nitric oxide(NO)and carcinoembryonic antigen(CEA) in patients with lung cancer,and to discuss the relationship between the NO and CEA.Methods:Serum NO and CEA were measured in 17 patients with lung cancer and 29 normal controls by improving Griess assay and radiol immunological assay respectively.Results:The levels of serum NO were significantly higher in patients with lung cancer than those in the control group( P < 0.01 ), the positive rates determining NO and CEA were 94.12% and 64.71%( P < 0.05 );Serum NO levels were positively correlated with those of CEA(r=0.815, P <0.01). Conclusion:It is suggested that the determination of serum NO is useful in diagnosis of lung cancer. |
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| Keywords: | lung cancer nitric oxide carcinoembryonic antigen |
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