| P物质对增生性瘢痕成纤维细胞增殖的影响 |
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| 引用本文： | 邓云川,李世荣,丛林. P物质对增生性瘢痕成纤维细胞增殖的影响[J]. 重庆医学, 2003, 32(5): 517-518 |
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| 作者姓名： | 邓云川 李世荣 丛林 |
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| 作者单位： | 第三军医大学西南医院整形外科中心,重庆,400038;第三军医大学西南医院整形外科中心,重庆,400038;第三军医大学西南医院整形外科中心,重庆,400038 |
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| 摘 要： | 目的 观察P物质对人增生性瘢痕成纤维细胞增殖的影响，探讨P物质在增生性瘢痕发生发展中的作用机制。方法 采用细胞培养技术，建立成纤维细胞系，应用细胞计数、MTT法及电镜进行形态学对比研究人增生性瘢痕成纤维细胞对P物质的反应。结果 P物质促进人增生性瘢痕成纤维细胞的生长。结论 P物质在增生性瘢痕的发生发展中起着重要的促进作用.
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| 关 键 词： | P物质 增生性瘢痕 成纤维细胞 |
| 文章编号： | 1671-8348(2003)05-0517-02 |
The influence of substance P on proliferation of fibroblasts derived from hypertrophic scars |
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| Deng Yun chuan,Li Shi rong,Cong Lin. The influence of substance P on proliferation of fibroblasts derived from hypertrophic scars[J]. Chongqing Medical Journal, 2003, 32(5): 517-518 |
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| Authors: | Deng Yun chuan Li Shi rong Cong Lin |
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| Abstract: | Objective To explore the influence of substance P on proliferation of fibroblasts derived from hypertrophic scars and the mechanism of substance P on the development of hypertrophic scars. Methods Cell strains were established by tissue culture technique. Cell counting, MTT method and electron microscopes were used to study the response of fibroblasts from hypertrophic scars to substance P. Results Substance P can increase the growth of fibroblasts from hypertrophic scars. Conclusion Substance P had important effects on the development of hypertrophic scars. |
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| Keywords: | substance P hypertrophic scars fibroblasts |
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