超声联合弹性成像在非哺乳期乳腺癌诊断中的应用价值分析

目的：研究超声联合弹性成像在非哺乳期乳腺癌诊断中的应用价值。方法选择105例乳腺病灶患者，按照术后病理或超声引导穿刺结果分为乳腺癌组（41例）与乳腺炎组（64例），两组均行超声、弹性成像检查，观察两组患者病灶影像学特征。结果两组患者共检出良性病灶68个，恶性病灶79个。良性病灶检出率最高为慢性乳腺炎（45.59%），恶性病灶中检出率最高的为浸润性导管癌（75.95%）。良性病灶多数未见微小钙化，钙化病灶内部呈小条状或斑点状回声，多数病灶后方回声未见明显衰减。恶性病灶多呈微小钙化，钙化病灶内多呈簇状或散在点状强回声，病灶后方回声多明显衰减，良、恶性病灶微小钙化及后方回声衰减情况检出率有统计学差异（P﹤0.05）。恶性病灶内部Ⅱ～Ⅲ级血流比例（82.28%）多于良性病灶（58.82%），差异有统计学意义（P﹤0.05）。恶性病灶血流多呈不规则穿入型血流信号，良性病灶周围血流信号程度不等。良性病灶弹性成像4～5分为20.59%，恶性病灶为91.14%，差异有统计学意义（P﹤0.05）。良性病灶RI≥0.70为26.47%，恶性病灶RI≥0.70为74.68%，差异有统计学意义（P﹤0.05）。常规超声恶性病灶诊断率（67.09%）低于常规超声联合弹性成像（86.08%），差异有统计学意义（P﹤0.05）。结论超声联合弹性成像在诊断乳腺良恶性病变上较单纯超声更具优势。

Application of ultrasound elastography in the diagnosis of breast cancer in non-lactating women

Objective To study the use of ultrasound elastography in the diagnosis of breast cancer in non-lactating women. Method 105 cases with breast lesions were included in the study, and were stratified as breast cancer group (n=41) and mastitis group (n=64) according to postoperative pathology or ultrasound-guided biopsy results, ultrasound elas-tography was administered in both groups to evaluate the imaging characteristics. Result A total of 68 benign lesions, and 79 malignant lesions were detected in both groups, with the highest detection rate of benign lesions in chronic masti-tis (45.59%), and that of malignant lesions in invasive ductal carcinoma (75.95%). Microcalcifications were rare in be-nign lesions, with little calcified lesions presenting strip-shaped or mottled echo texture, and most benign lesions had pos-terior echo that were not attenuated. Malignant lesions were basically of microcalcifications, with calcified lesions pre-senting mainly as clustered or scattered echo, and posterior echo were attenuated, and the microcalcifications and attenua-tions of posterior echo in benign and malignant lesions were of statistically significant difference (P<0.05). Proportion of grade II-III blood flow within the malignant lesions (82.28%) was more than that in the benign lesions (58.82%) (P<0.05). The blood flow presented essentially irregular and crossing signals in malignant lesions, while inconsistent periph-eral blood flow signals were observed in benign lesions. 20.59%of benign lesions had elastography score at 4~5, while in malignant lesion the percentage was 91.14%(P<0.05). RI≥0.70 in begin lesions was 26.47%, while was 74.68%in ma-lignant lesions (P<0.05). Conventional ultrasound was inferior in the diagnosis of malignant lesions (67.09%) than ultra-sound elastography (86.08%), with significant differences observed (P<0.05). Conclusion Ultrasound elastography is su-perior in the diagnosis of benign and malignant breast disease.