Nonvaccine Streptococcus pneumoniae serotypes causing acute bacterial meningitis |
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Authors: | Luque Moreno A Bergadà Masó A Sin Opi J M Liarte Guillén A Mayol L Macià Martí J |
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Institution: | Servicio de Pediatría, Hospital Universitario de Girona Doctor Josep Trueta, Girona, Spain. DRLUKE69@hotmail.com |
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Abstract: | The pneumococcal heptavalent conjugate vaccine protects children aged less than 2 years old from invasive pneumococcal disease (IPD). Efficacy is 89-93% in the US population and 71-86% in European studies. The vaccine confers active immunization against the main serotypes causing IPD (4, 6B, 9V, 14, 18C, 19F y 23F). We describe 2 children who presented with pneumococcal meningitis caused by nonvaccine serotypes. As a result of the widespread use of the heptavalent vaccine, there may be a shift in the serotypes causing IPD. |
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