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THE ROLE OF THE RENAL NERVES IN RENIN SYNTHESIS
Authors:Yanling Zhang  Trefor Morgan  Gullvig Read
Affiliation:Department of Physiology, University of Melbourne, Victoria, Australia.
Abstract:1. Renin synthesis and secretion were studied in Balb/c mice with a denervated left kidney. 2. Denervation inhibited renin secretion. 3. Denervation reduced the renal renin content. 4. Denervation reduced renal renin mRNA. 5. Renal denervation inhibits renin secretion by blocking the synthetic system prior to mRNA formation.
Keywords:mRNA    renal nerves    renin    renin release    renin synthesis
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