The effects of administrations of HCI, NH4CI and NH4HCO3 on the excretion of urea and ammonium in man |
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| Authors: | ADRIAN FINE J E CARLYLE E BOURKE |
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| Institution: | Renal Unit, University Department of Medicine, and Biochemistry Department, Royal Infirmary, Glasgow, Scotland, and Department of Clinical Medicine, Meath Hospital, Dublin, Ireland |
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| Abstract: | In man, HCl acidosis reduces blood and urinary urea with a concomitant rise in ammonium (NH4+) excretion. Significantly less urea is excreted following NH4Cl administration than following equimolar ingestion of NH4 HCO3. The results of these alterations in nitrogen excretion are interpreted in terms of bicarbonate utilization and production. |
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