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江南卷柏中双黄酮类化学成分研究
引用本文:邹振兴,徐康平,邹辉,张琼,刘敏桢,谭桂山.江南卷柏中双黄酮类化学成分研究[J].中南药学,2012,10(1):4-6.
作者姓名:邹振兴  徐康平  邹辉  张琼  刘敏桢  谭桂山
作者单位:1. 中南大学药学院,长沙,410013
2. 中南大学药学院,长沙410013;中南大学湘雅医院,长沙410008
基金项目:国家自然科学基金(No.30873149)
摘    要:目的 研究江南卷柏中的双黄酮类成分.方法 利用色谱法对江南卷柏75%醇提部分的化学成分进行系统分离纯化,利用理化性质及核磁共振图谱等手段对分离得到的单体化合物进行结构鉴定.结果 从江南卷柏中分离得到了5个化合物,分别为穗花杉双黄酮( ametoflavone,1),罗巴斯塔双黄酮-4 ’-甲醚(4’-O-methylrobustaflavone,2),穗花杉双黄酮-4 ’甲醚(4'-O-methylametoflavone,3),穗花杉双黄酮-7-甲醚(7-O-methylametoflavone,4),7,4'-二甲氧基穗花杉双黄酮(7,4 ’-di- O-methylametoflavone,5).结论 其中化合物4为首次从江南卷柏中分离得到.

关 键 词:江南卷柏  化学成分  双黄酮类化合物

Biflavonoids from Selaginella moellendorfii Hieron
ZOU Zhen-xing , XU Kang-ping , ZOU Hui , ZHANG Qiong , LIU Min-zhen , TAN Gui-shan.Biflavonoids from Selaginella moellendorfii Hieron[J].Central South Pharmacy,2012,10(1):4-6.
Authors:ZOU Zhen-xing  XU Kang-ping  ZOU Hui  ZHANG Qiong  LIU Min-zhen  TAN Gui-shan
Institution:1,2*(1.School of Phatmaceutical Sciences,Central South University,Changsha 410013;2.Xiangya Hospital,Central South University,Changsha 410008)
Abstract:Objective To study biflavonoids from Selaginella mellendorfii Hieron. Methods The constituents were isolated and purified by several column chromatographic methods,and their structures were identified by their physicochemical properties and spectrum. Results Five compounds were isolated from Selaginella mellendorfii Hieron and elucidated as ametoflavone(1),4′-O-methylrobustaflavone(2),4′-O-methylametoflavone(3),7-O-methylametoflavone(4),and 7,4′-di-O-methylametoflavone(5). Conclusion Compound 4 has been isolated from Selaginella mellendorfii Hieron for the first time.
Keywords:Selaginella moellendorfii  chemical constituents  biflavonoids
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