丁苯酞治疗血管性认知功能障碍的疗效观察

目的 观察丁苯酞治疗血管性认知功能障碍的疗效.方法 将62例脑卒中后血管性认知功能障碍患者按随机原则分为治疗组32例,对照组30例,治疗组采用常规内科治疗和丁苯酞治疗,对照组采用常规内科治疗,疗程均为8周,在治疗4周和8周后对2组的疗效进行评估.结果 治疗组治疗后的MMSE评分显著高于对照组(P＜0.01)；治疗组治疗后的MoCA评分亦显著高于对照组(P＜0.05).结论 丁苯酞能改善轻-中度血管性认知功能障碍患者的认知损害.

Clinical efficacy of butylphthalide for vascular cognitive impairment

Objective To observe the clinical efficacy of butylphthalide in the treatment of vascular cognitive impairment.Methods A total of 62 patients with vascular cognitive impairment were randomly divided into a treatment group and a control group(32 patients in the treatment group and 30 the other in the control group).The treatment group used both the conventional medical treatment and therapy butylphthalide,while the control group only used the conventional treatment for 8 weeks.After the 4 week and 8 week treatment,we evaluated the clinical efficacy of the 2 groups.Results After the treatment,scores of MMSE(P<0.01) and MoCA(P<0.05) in the treatment group increased significantly.Conclusion Butylphthalide can improve the cognitive function in patients with mild-moderate vascular cognitive impairment.