| 长链非编码RNA在结直肠癌诊断及预后中的研究进展 |
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| 引用本文： | 霍超(综述),方学红(综述),蒋代顺(综述),刘义(审校). 长链非编码RNA在结直肠癌诊断及预后中的研究进展[J]. 临床与病理杂志, 2022, 0(1) |
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| 作者姓名： | 霍超(综述) 方学红(综述) 蒋代顺(综述) 刘义(审校) |
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| 作者单位： | 广东医科大学广东天然药物研究与开发重点实验室;广东医科大学药学院 |
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| 基金项目： | 广东省自然科学基金(2018A0303130252)。 |
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| 摘 要： | 早期诊断和预后标志物的缺乏是导致结直肠癌(colorectal cancer,CRC)患者生存率低的主要原因。长链非编码RNA(long non-coding RNA,lncRNA)由于在CRC发生发展中发挥重要的作用,并且能在外周血中稳定存在,而被认为是具有潜在临床应用价值的生物标志物。
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| 关 键 词： | 结直肠癌 长链非编码RNA 早期诊断 预后 生物标志物 |
Research progress of long non-coding RNA in the diagnosis and prognosis of colorectal cancer |
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| Affiliation: | (Guangdong Key Laboratory for Research and Development of Natural Drugs,Guangdong Medical University,Zhanjiang Guangdong 524023;School of Pharmacy,Guangdong Medical University,Zhanjiang Guangdong 524023,China) |
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| Abstract: | Colorectal cancer(CRC)is the third most common malignant tumor worldwide.The lack of early diagnosis and prognostic markers are the main reasons for the low survival rate of CRC patients.Long non-coding RNA(lncRNA)is considered a biomarker with potential clinical application due to its important role in the occurrence and development of CRC and its stable presence in peripheral blood. |
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| Keywords: | colorectal cancer long non-coding RNA early diagnosis prognosis biomarkers |
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