Wound dehiscence and stump infection after lower limb amputation: risk factors and association with antibiotic use |
| |
Authors: | Nathalie Dunkel Ilker Uçkay Wilson Belaieff Mathieu Assal Valentina Corni Alain Lacraz Şaziye Karaca |
| |
Affiliation: | 1. Department of Infectious Diseases, Geneva University Hospitals & Medical School, University of Geneva, Geneva, Switzerland 2. Orthopaedic Surgery Department, Geneva University Hospitals & Medical School, University of Geneva, 4, rue Gabrielle Perret-Gentil, 1211, Geneva 14, Switzerland 3. Department of Cardiovascular Surgery, Geneva University Hospitals & Medical School, University of Geneva, Geneva, Switzerland
|
| |
Abstract: | BackgroundOptimal duration of antibiotic prophylaxis following major lower limb amputation in preventing adverse stump outcomes is controversial.ObjectiveWe assess the epidemiology and risk factors of wound dehiscence and stump infection after mid-thigh to transmetatarsal amputations with regard to antibiotic administration.MethodsOur retrospective observational study at the Geneva University Hospital (January 1995–June 2010) includes a total of 289 amputations in 270 adult patients (199 males; median age 70 years).ResultsWound dehiscence and/or stump infection occurred in 47 (16.3 %) and 63 (21.8 %) patients with a median delay of 24 and 14 days, respectively. No clinical variable was significantly associated with stump infection. Diabetes and older age (>80 years) were associated with dehiscence. Importantly, transcutaneous tissue oxygen tension (TcPO2) and duration of antibiotic administration showed no association with either outcome.ConclusionThe duration of antibiotic administration before or after surgery does not change the epidemiology of stump complications. |
| |
Keywords: | |
本文献已被 ScienceDirect SpringerLink 等数据库收录! |
|