| 胰岛素对大脑皮质损伤后胶质细胞和AchE纤维变化的影响 |
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| 引用本文： | 徐杰,王春,侯春莲. 胰岛素对大脑皮质损伤后胶质细胞和AchE纤维变化的影响[J]. 解剖学研究, 1996, 0(2) |
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| 作者姓名： | 徐杰 王春 侯春莲 |
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| 作者单位： | 蚌埠医学院解剖教研室!蚌埠233003(徐杰，王春)，蚌医附属医院供应室!蚌埠233003(侯春莲) |
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| 摘 要： | 本实验采用SD大鼠56只,于顶皮质作一宽2mm的冠状切口,用尼氏染色和AchE阳性纤维染色,观察损伤后胰岛素对切口两侧胶质细胞变化的影响.结果:损伤组和损伤用药组损伤切口两侧的胶质细胞在1～2W内迅速增生和集聚;2～3W出现胶质瘢痕,4～8W内增生的胶质细胞减少,胶质瘢痕收缩成一条致密带,再生胆碱能纤维沿切口两侧生长,难以穿越瘢痕组织,胰岛素用药组皮质损伤切口两侧的胶质细胞增生虽较损伤组轻,但还不足以有效的抑制胶质瘢痕的形成.
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| 关 键 词： | 神经胶质细胞 大脑皮质 损伤 胰岛素 |
THE EFFECT OF INSULIN ON THE CHANGES OF GLIAL CELLS AND CHOLINERGIC FIBERS AFTER THE CEREBRAL CORTEX LESION |
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| Xu Jie Hou Chunlian. THE EFFECT OF INSULIN ON THE CHANGES OF GLIAL CELLS AND CHOLINERGIC FIBERS AFTER THE CEREBRAL CORTEX LESION[J]. Anatomy Research, 1996, 0(2) |
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| Authors: | Xu Jie Hou Chunlian |
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| Abstract: | 56 SD rats(two month old) were operated wtih a incision at the parietal cortex. Nissl and AchE staining methods were used for observing the effect of insulin on the changes of glia and cholinergic fibers. The results showed that as follow: in both the damage rats and the damage rats with insulin injection , the number of the glial cells at the both side of the incision increase rapidly in 1~2 weeks after lesion. And the glial scar appears in 3~4 weeks. However, the num-bet of the glial cells decrease in 4-8 weeks . A band of glial scar forms at this time and the AchE fibers can not pass through the glial scar. Although insulin can reduce the glial reaction after cortex damage, it can not stop the formation of glial scar. |
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| Keywords: | glia cells cerebral cortex injury insulin |
| 本文献已被 CNKI 等数据库收录！ |
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