首都医科大学附属北京妇产医院近40年宫颈癌发病特点及趋势分析

目的 探讨首都医科大学附属北京妇产医院近40年宫颈癌住院患者的发病特点及趋势的变化.方法 回顾性分析我院1979年1月至2018年12月期间收治的6426例宫颈癌患者的病例资料,根据入院时间不同,划分为两组即1979～1998年组(前20年)和1999～2018年组(后20年),统计分析两组不同年限的患者在发病年龄、肿...

Analysis of the characteristics and trend of cervical cancer incidence in Beijing Obstetrics and Gynecology Hospital,Capital Medical University over the past 40 years

Objective To investigate the changes in the incidence characteristics and trends of cervical cancer patients in Beijing Obstetrics and Gynecology Hospital,Capital Medical University over the past 40 years.Methods The data of 6426 patients with cervical cancer admitted to our hospital from January 1979 to December 2018 were retrospectively analyzed.According to the different admission time,they were divided into two groups,namely the group from 1979 to 1998 and the group from 1999 to 2018.Statistical analysis of the two groups of patients with different years of age,tumor stage and pathological changes.Results 2346 cases were included in the group from 1979 to 1998,and 4080 cases were included in the group from 1999 to 2018.The age of cervical cancer incidence in the group from 1979 to 1998 was 55~64 years old(42.97%),and that in the group from 1999 to 2018 was 45~54 years old(41.08%).Cervical cancer in the 45~54 years old increased from 22.04%20 years ago to 41.08%;cervical cancer in the 55~64 years old group decreased from 42.97%20 years ago to 18.21%;cervical cancer in the>65 years old group decreased from 24.72%20 years ago to 6.96%,all of which were statistically significant(P<0.05).In terms of FIGO staging,the proportion of early cervical cancer(stage IA1-IIA)increased from 21.82%20 years ago to 52.18%,and the proportion of advanced cervical cancer(stage IIB-IV)decreased from 76.94%20 years ago to 41.89%,with statistically significant differences(P<0.05).In terms of pathological types,squamous cell carcinoma was the main type,but squamous cell carcinoma decreased to 80.25%from 95.01%20 years ago.Adenocarcinoma and cancer of special pathological type increased from 3.37%and 0.68%20 years ago to 17.19%and 1.58%,with statistically significant differences(P<0.05).Conclusion The total number of cervical cancer patients in our hospital has been on the rise over the past 40 years.The incidence of cervical cancer tends to be younger and more early in the past 20 years.The incidence of cervical adenocarcinoma and special tissue type cancer increased.