乳腺癌病人腋窝淋巴结转移相关因素分析

目的分析乳腺癌病人的临床及病理学特征，探寻乳腺癌病人腋窝淋巴结转移的相关因素。方法回顾性分析105例行外科手术治疗并经病理学确诊为乳腺癌的新发女性病例的临床及病理学资料。分析影响腋窝淋巴结转移的相关因素。结果105例病人中有45例（42.9%）发生了腋窝淋巴结转移。不同年龄、肿瘤长径、肿瘤部位、组织学分级、病理类型及有无脉管癌栓浸润的乳腺癌病人，腋窝淋巴结转移率差异均有统计学意义（P < 0.05~P < 0.01）；多因素logistic分析结果显示，肿瘤长径越长、有脉管癌栓浸润是乳腺癌腋窝淋巴结转移的独立危险因素（P < 0.05）。结论肿瘤长径和脉管癌栓浸润是腋窝淋巴结转移的独立危险因素。

Analysis of the related factors of axillary lymph node metastasis in patients with breast cancer

ObjectiveTo analyze the clinicopathological features of breast cancer, and explore the related factors of axillary lymph node metastasis in patients with breast cancer.MethodsThe clinical data of 105 breast cancer patients treated with operation, and diagnosed by pathology, were retrospectively analyzed.The relative factors of axillary lymph node metastasis were investigated.ResultsAmong 105 patients, 45 cases with axillary lymph node metastasis were found, and the metastasis rate was 42.9%.The differences of the age, tumor length, tumor location, histological grade, pathological type, vascular cancer embolus infiltration and axillary lymph node metastasis rate in breast cancer patients were statistically significant(P < 0.05 to P < 0.01).The results of multivariate logistic analysis showed that the long tumor in length diameter and vascular cancer embolus infiltration were the independent risk factors of axillary lymph node metastasis in breast cancer(P < 0.05).ConclusionsThe length diameter of tumor size and tumor vascular invasion are the independent risk factors of axillary lymph node metastasis.