| 地衣芽孢杆菌对肝硬化亚临床肝性脑病患者的影响 |
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| 引用本文： | 舒敏,车宇光. 地衣芽孢杆菌对肝硬化亚临床肝性脑病患者的影响[J]. 实用全科医学, 2008, 6(11): 1119-1120 |
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| 作者姓名： | 舒敏 车宇光 |
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| 作者单位： | [1]辽宁省大连大学中山医院消化科,116001 [2]辽宁省大连市第二人民医院消化科,116001 |
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| 摘 要： | 目的探讨地衣芽孢杆菌（整肠生）对肝硬化亚临床肝性脑病（SHE）患者肠道菌群、血氨、肝功能的影响。方法将62例经数字连接试验（NCT）、数字符号试验（DST）检查异常的SHE患者按所在医院分组，A组（中山医院组）为治疗组（32例），给予地衣芽孢杆菌0．5g和复合维生素B2片，3次／d，口服；B组（第二人民医院组）为对照组（30例），给予复合维生素B2片，3次／d，口服。两组均服药4周。在服药前及第4周末随访，作血氨、肠道菌群（肠球菌、双歧杆菌）菌落计数，NCT、DST检测并观察肝性脑病（HE）的发病率。结果治疗后双歧杆菌由（8．56±4．04）logn／g增至（10．91±1．35）logn／g，血氨水平降低，NCT、DST、肝性脑病发病率差异均有统计学意义。结论地衣芽孢杆菌能降低肝硬化患者血氨水平，改善肠道菌群失调，改善智力测验和降低HE发病率。
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| 关 键 词： | 亚临床肝性脑病 地衣芽孢杆 治疗 |
Curative Effects of Bacillus Licheniformis Capsule on Course of subclinical Hepalic Encephalopathy |
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| SHU Min,CHE Yu-guang. Curative Effects of Bacillus Licheniformis Capsule on Course of subclinical Hepalic Encephalopathy[J]. Applied Journal Of General Practice, 2008, 6(11): 1119-1120 |
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| Authors: | SHU Min CHE Yu-guang |
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| Affiliation: | SHU Min, CHE Yu- guang. (Department of Gastroenterology, Zhongshan Hospital Affiliated to Dalian University, Liaoning 116001, China) |
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| Abstract: | Objective To study the curative effects of Bacillus Licheniformis Capsule on the intestinal dysbacteriosis,blood ammonia and liver function in liver cirrhosis patients with subclinical hepatic encephalopathy(SHE).Methods Sixty-two SHE patients conformed by number connection test(NCT) and digital symbol test(DST) were randomly divided into two groups: group A(treatment group,32 cases in Zhongshan Hospital) was treated with Bacillus Licheniformis Capsule and vitamin B complex for 4 weeks;group B(Control group... |
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| Keywords: | Subclinical hepatic encephalopathy Bacillus Licheniformis Capsule Therapy |
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