人附红细胞体的电镜观察及临床特征研究

目的：进一步研究人附红细胞体（EH）的电镜特点及EH的感染率、发病 率和临床特点。方法：选择门诊及病房患者187例，观察末梢血涂片附红体感染强度；选择8例EH病，2例EH重度感染者的静脉血进行扫描电镜观察。结果：本组附红体感染率为81.8%，发病率为5.2%；扫描电 镜下EH呈多形性小体，球形多见，直径为0.3-1.5μm寄生于成熟红细胞表面，寄生EH的红细胞表面出现皱褶、突起、凹陷，大型EH带有纤丝扒嵌在红细胞膜下。结论：非健康人群的EH感染率很高，电镜观察显示被EH寄生的红细胞可发生膜的改变，是导致EH病发生溶血的原因之一，大量附红体寄生于红细胞上，使糖代谢发生改变，导致血糖下降；尽管血涂片转阴，但电镜下仍可见到少量EH存在。

Characteristics of eperythrozoon-humani under the electron microscope and clinical mainifestation

Objective:To study the electron microscope and clinical manifestation.Methods:187 patients' peripheral blood from the clinic and hospitalization were observed by light microscope and the concentration of eperythrozoon's infection was defined,vein samples were detected by scanning electron microscope.Result:The rate of infection is about 81.8%,the morbidity is about 5.2%.eperythrozoons were showed that they were spherical corpuscles which parasitized on the surface or the mature erythrocytes,there were folds of protrudings in the surface of the erythrocytes which were attached by eperythrozoons.eperythrozoo's diameter is between 0.3um to 1.5um and large eperythrozoons have the fibrils that attached the membrance of the erythrocytes.Conclusion:eperythrozoonsis is a anthropozoonsis,unhealth human group is susceptible to eperythrozoon.The membrance of the erythrocytes parasitized by the eperythrozoons could be changed such as folds,pits and holes that could be related to the hemolysis.the changing of the glucose's metabolism could lead to the low level of blood sugar while a large mumber erythrocytes were parasitized by eperythrozoon. [