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不同含量铜、锌、锡离子金属抑菌性能测定
引用本文:刘春霞,曹小秋,刘立华.不同含量铜、锌、锡离子金属抑菌性能测定[J].实验与检验医学,2012,30(3):227-229.
作者姓名:刘春霞  曹小秋  刘立华
作者单位:1. 江苏省南通瑞慈医院检验科,江苏南通,226010
2. 上海同普放射防护设备有限公司,上海,200033
摘    要:目的 了解不同含量的铜、锌、锡金属板(1号、2号、3号)对不同种细菌的抑制作用及比较.方法 取1ml不同浓度菌悬液混入4ml 56℃营养琼脂液中,浇注到1~3号金属板和阳性对照中,浇注量为1ml/板,37℃孵育24~72h,观察细菌生长情况.结果 紫铜和黄铜对金黄色葡萄球菌(ATCC25923)、大肠埃希菌(ATCC25922)和临床分离菌株抑菌能力较好,均无细菌生长,青铜次之;紫铜对白假丝酵母菌有很好的抑茵作用,均无细菌生长,青铜和黄铜对白假丝酵母茵抑菌效果较差,3种金属板对铜绿假单胞菌抑菌效果均较差.结论 不同含量的铜、锌、锡金属板因各自成分不同,对不同种细菌的抑制作用也各不相同,可为医疗消毒领域提供参考.

关 键 词:金属离子  抗菌作用  细菌

Bacteriostatic effect of different concentrations of Cu2+,Zn2+ and Sn2+
LIU Chunxia , CAO Xiaoqiu , LIU Lihua.Bacteriostatic effect of different concentrations of Cu2+,Zn2+ and Sn2+[J].Experimental and Laboratory Medicine,2012,30(3):227-229.
Authors:LIU Chunxia  CAO Xiaoqiu  LIU Lihua
Institution:.Department of Clinical Laboratory,the Rich Hospital of Nantong,Nantong Jiangsu 226010,China
Abstract:Objective To observe bacteriostatic effect of metal board with different concentrations of Cu2+,Zn2+ and Sn2+(corresponding to metal board 1,2 and 3 respectively).Methods After mixing 1 ml bacterial suspension with 4 ml agar solution(56℃) evenly and completely,then 1 ml mixture was poured into the tests and control metal board respectively.The boards were incubated at 37℃ for 24-72h.Results Metal board 1 and 3 showed higher antimicrobic properties for Staphylococcus aureus and Escherichia coli.Metal board 1 showed higher antimicrobic properties for Candida albicans.Metal board 1-3 showed low antimicrobic properties for Pseudomonas aeruginosa.Conclusion The metal boards with different concentrations of Cu2+,Zn2+ and Sn2+ have different antimicrobic properties for different bacterium.It provided a reference for disinfection in medical field.
Keywords:Metal ions  Bacteriostatic effect  Bacterium
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