| 羟基喜树碱联合IL-2治疗恶性腹腔积液的疗效观察 |
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| 引用本文： | 董灵,赵全德,李向东,宋怡兵,黄小玲. 羟基喜树碱联合IL-2治疗恶性腹腔积液的疗效观察[J]. 现代肿瘤医学, 2007, 15(7): 974-975 |
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| 作者姓名： | 董灵 赵全德 李向东 宋怡兵 黄小玲 |
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| 作者单位： | 四川省阆中市人民医院肿瘤科,四川,阆中,637400 |
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| 摘 要： | 目的:观察羟基喜树碱(HCPT)联合重组人白介素-2(IL-2)治疗恶性腹腔积液的疗效。方法:将24例恶性腹腔积液的患者置管放净腹水后,经导管注入NS40ml HCTP20mg,NS40ml IL-2100万单位,每周1～2次,观察总有效率及毒副反应。结果:24例患者总有效率为95.9%,腹痛4.1%,骨髓抑制发生率70.8%,均为Ⅰ°～Ⅱ°,发热8.3%,脱发100%,恶心75%,无呕吐,未见心电图及肝肾功能异常。结论:羟基喜树碱联合IL-2治疗恶性腹腔积液疗效好,副反应轻,值得推广。
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| 关 键 词： | 恶性腹腔积液 羟基喜树碱 重组人白介素-2 |
| 文章编号： | 1672-4992-（2007）07-974-02 |
| 修稿时间： | 2006-10-19 |
Efficacy of combined HCPT with IL-2 in the treatment of malignant ascites of abdominal cavity |
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| DONG Ling,ZHAO Quan-de,LI Xiang-dong,SONG Yi-bing,HUANG Xiao-ling. Efficacy of combined HCPT with IL-2 in the treatment of malignant ascites of abdominal cavity[J]. Journal of Modern Oncology, 2007, 15(7): 974-975 |
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| Authors: | DONG Ling ZHAO Quan-de LI Xiang-dong SONG Yi-bing HUANG Xiao-ling |
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| Affiliation: | Department of oneology , the Hospital of Langzhong , Sichuan 637400, China |
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| Abstract: | Objective:Combine HCPT with IL-2 to cure malignant ascites of abdominal cavity and observe the curative effect.Methods:To put tubes into the abdomen of 24 patients with malignant ascites of abdominal cavity and absord the water completely,then inject NS40ml HCPT 20 mg NS40ml IL-2 100u.Results:In the 24 patients,the total effetiverate was 95.9% ;bellyache 4.1%,the occurrence of marrow inhibiting rate was 70.8%,falling of air:100%,nausea:75%,liver and kidney function were normal.Conclusion:Combine HCPT with IL-2 to cure malignait precipitate of abdominal cavity can get a good curative effects. |
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| Keywords: | malignant ascites of abdominal cavity hydroxycamptuthecin recombine IL - 2 |
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