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| 红车轴草化学成分的研究 | |
| 引用本文： | 马强,雷海民,周玉新,王长海. 红车轴草化学成分的研究[J]. 中国药学杂志, 2005, 40(14): 1057-1058 |
| 作者姓名： | 马强 雷海民 周玉新 王长海 |
| 作者单位： | 1. 大连理工大学环境与生命学院生物科学与工程系,辽宁,大连,116024 2. 北京中医药大学中药学院,北京,100102 3. 北京美德森医药技术开发有限公司,北京,100029 |
| 摘 要： | 目的对红车轴草(Trifolium pratense L.)的化学成分进行研究。方法应用硅胶柱层析和Sephadex LH-20凝胶柱层析对化合物进行分离,通过理化和波谱分析方法鉴定其结构。结果从红车轴草中分离得到8个化合物,分别鉴定为十八烷醇(Ⅰ)、5-羟基-7,4′-二甲氧基异黄酮(Ⅱ)、鹰嘴豆芽素A(Ⅲ)、樱黄素(Ⅳ)、芒柄花素(Ⅴ)、染料木素(Ⅵ)、芒柄花苷(Ⅶ)和大豆苷元(Ⅷ)。结论化合物Ⅰ和Ⅱ为首次从该植物中得到。 |
| 关 键 词： | 红车轴草 化学成分 |
| 文章编号： | 1001-2494（2005）14-1057-03 |
| 收稿时间： | 2004-08-31 |
| 修稿时间： | 2004-08-31 |
Studies on chemical constituents of Trifolium pratense |
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| MA Qiang,LEI Hai-min,ZHOU Yu-xin,WANG Chang-hai. Studies on chemical constituents of Trifolium pratense[J]. Chinese Pharmaceutical Journal, 2005, 40(14): 1057-1058 | |
| Authors: | MA Qiang LEI Hai-min ZHOU Yu-xin WANG Chang-hai |
| Affiliation: | 1. Department of Bioscience and Biotechnology， School of Environmental and Biological Science and Technology， Dalian University of Technology， Dalian 116024， China； 2.Beijing University of Chinese Medicine， Beijing 100102， China； 3.Beijing MedSun Pharmaceuticals Co.，Ltd，Beijing 100029，China |
| Abstract: | OBJECTIVE To study the chemical constituents of Trifolium pratense L. . METHODS The constituents were isolated and purified by chromatography with silica gel column and Sephadex LH-20 gel column, then identified by physicochemical properties and structurally elucidated by spectral analysis. RESULTS Eight compounds were obtained from Trifolium pratense L. and identified as 1-octadecanol (Ⅰ), 5-hydroxy-7,4′-dimethoxyisoflavone(Ⅱ) , biochanin A(Ⅲ) , prunetin(Ⅳ) , formononetin (Ⅴ) , genistein (Ⅵ) , ononin (Ⅶ) and daidzein (Ⅷ) .CONCLUSION Compound Ⅰ and Ⅱ are found in this plant for the first time. |
| Keywords: | Trifolium pratense L. chemical constituents |
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