基于Caprini评分的肝切除术患者静脉血栓栓塞风险因素分析

目的以Caprini风险评估模型评分为参考分析肝切除术患者术后发生静脉血栓栓塞症的危险因素。方法采用回顾性研究方法,收集本院310例接受肝切除手术患者的临床资料,以Caprini风险评估模型进行评分,并通过单因素及多因素分析,对Caprini风险评估模型中的危险因素及肝切除手术相关因素进行筛选,发现影响肝切除术患者静脉血栓栓塞症风险的危险因素。结果单因素及多因素Logistic回归分析显示,手术时间3h、肝恶性肿瘤、深静脉血栓和(或)肺栓塞史为肝切除手术患者发生静脉血栓栓塞症的独立危险因素。Caprini风险评估模型评分静脉血栓栓塞症组患者得分(6.77±1.81)分,非静脉血栓栓塞症组得分(3.62±2.25)分(P=0.02)。Caprini风险评估模型评分≥7分时,发生静脉血栓栓塞症的风险明显增加。结论肝切除术患者术后静脉血栓栓塞症发生的危险因素是手术时间3h、肝恶性肿瘤、深静脉血栓和(或)肺栓塞史,随着Caprini评分的增加静脉血栓栓塞症的风险逐渐升高。

Risk factor analysis based on Caprini score on venous thromboembolism for patients after hepatectomy

Objective To analyze risk factors of venous thromboembolism after hepatectomy referring to Caprini risk assessment model.Method Collect clinical information of 310 patients receiving hepatectomy in this hospital and assess them by Caprini risk assessment model using retrospective research method.Screen risk factors and related factors of hepatectomy in Caprini risk assessment model and find out the risk factors of venous thromboembolism after hepatectomy by single and multiple factor analysis.Result Single and multiple Logistic regression analysis show that more than 3h of surgery time,liver malignant tumor,deep venous thrombosis and (or) pulmonary embolism history are independent risk factors of venous thromboembolism after hepatectomy.Scores on Caprini risk assessment model are (6.77±1.81) in venous thromboembolism group and (3.62±2.25) in non-venous thromboembolism group (P=0.02).Risk of venous thromboembolism increases obviously when score on Caprini risk assessment model is more than 7.Conclusion More than 3h of surgery time,liver malignant tumor,deep venous thrombosis and (or) pulmonary embolism history are risk factors of venous thromboembolism after hepatectomy.The higher score on Caprini risk assessment model indicates higher risk on venous thromboembolism.