宫颈癌患者放射治疗后中长期生活质量现状及影响因素分析

目的评估宫颈癌患者放射治疗后中长期生活质量,探讨可能的影响因素,为改善其生活质量提供依据。方法采用宫颈癌生活质量评估量表对1 084例放射治疗后13~36个月的宫颈癌患者进行调查、分析。结果患者生活质量总分为(126.84±16.01)分,其中生理状况(24.48±4.19)分,社会/家庭状况(17.96±3.64)分,情感状况(20.17±3.62)分,功能状况(19.24±4.52)分,宫颈癌特异模块(44.99±3.77)分。单因素分析显示,家庭月收入、婚姻状况、性生活、年龄、肿瘤分期、放射治疗相关后遗症之间的差异均有统计学意义(P0.05)。多因素分析表明,肠道功能紊乱、性生活、婚姻状况是患者生活质量的最主要影响因素,其次是膀胱功能紊乱、下肢水肿、更年期症状、肿瘤分期。结论宫颈癌患者放射治疗后中长期生活质量受多种因素影响,应针对影响因素做好健康管理,提高其生活质量。

present situation of mid-long term quality of life for cervical cancer patients after radiotherapy and analysis on its influencing factors

Objective To evaluate the mid-long term quality of life for cervical cancer patients after radiotherapy and analyze its possible influencing factors to provide reference for improving their quality of life.Method Investigate and analysis on 1084 cervical cancer patients 13～36 months after radiotherapy by Functional Assessment of Cancer Therapy-Cervix (FACT-Cx).Result The total score on patients' quality of life is (126.84 ± 16.01).Scores on physiological status is (24.48±4.19),social/family status is (17.96 ± 3.64),emotion status is (20.17 ± 3.62),functional status is (19.24± 4.52) and specific module of cervical cancer is (44.99±3.77).Single factor analysis shows that the difference between different family income,marriage,sexual life,age,neoplasm staging and related sequela after radiotherapy are significant (P＜0.05).Multivariate analysis shows that intestinal dysfunction,sexual life and marriage are the main influencing factors of patients' quality of life.Bladder dysfunction,lower extremity edema,climacteric symptom and neoplasm staging are less important influencing factors.Conclusion Mid-long term quality of life for cervical cancer patients after radiotherapy is influenced by many factors.Health management according to influencing factors should be enhanced to improve patients' quality of life.