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山银花的研究进展及其质量标志物预测分析
引用本文:朱香梅,李晴,石雨荷,朱珏,童巧珍.山银花的研究进展及其质量标志物预测分析[J].世界中医药,2022(13).
作者姓名:朱香梅  李晴  石雨荷  朱珏  童巧珍
作者单位:1 湖南中医药大学药学院,长沙,410208; 2 湘产大宗道地药材种质资源及规范化种植重点研究室,长沙,410208; 3 岳阳市中医医院,岳阳,414000
基金项目:中央引导地方科技发展专项资金项目(2020ZYQ045);湖南省科学技术厅重点项目(2017SK2124)
摘    要:山银花为常用的大宗药材,始载于《名医别录》,被列为上品。山银花种质资源丰富,分布区域广,一直以来是多种中成药的主要原料,具有广阔的开发利用前景。山银花丰富的化学成分和多样的药理活性,使其在医疗、保健、美容等各方面应用广泛,但山银花品质评价研究仍有所欠缺,还需不断地完善。在对其化学成分、药理作用综述的基础上,结合中药质量标志物核心理论,从化学成分特有性、药代动力学、传统功效、传统药性、不同配伍及不同加工条件等几个方面对山银花的质量标志物进行预测分析,为山银花质量评价研究提供可靠的参考依据。

关 键 词:山银花  化学成分  药理作用  质量标志物
收稿时间:2021/5/24 0:00:00

Research Progress in Flos Lonicerae Confusae and Prediction of the Q-marker
ZHU Xiangmei,LI Qing,SHI Yuhe,ZHU Jue,TONG Qiaozhen.Research Progress in Flos Lonicerae Confusae and Prediction of the Q-marker[J].World Chinese Medicine,2022(13).
Authors:ZHU Xiangmei  LI Qing  SHI Yuhe  ZHU Jue  TONG Qiaozhen
Institution:1 School of Pharmacy,Hunan University of Chinese Medicine,Changsha 410208,China; 2 Key Laboratory of Germplasm Resources and Standardized Planting of Bulk Authentic Medicinal Materials from Hunan,Changsha 410208,China; 3 Yueyang Traditional Chinese Medicine Hospital,Yueyang 414000,China
Abstract:Flos Lonicerae Confusae,a common bulk medicinal,originated from Miscellaneous Records of Famous Physicians as the top grade.With abundant germplasm resources and wide distribution,it has always been the main raw material of a variety of Chinese patent medicines and has broad prospects for development and utilization.The rich chemical components and diverse pharmacological activities enable it to be applied in medical treatment,health care,beauty,and other aspects.However,research on the quality evaluation of Flos Lonicerae Confusae should be further improved.Therefore,this study summarized the chemical composition and pharmacological effects of Flos Lonicerae Confusae and predicted the Q-markers of it based on the unique chemical components,pharmacokinetics,conventional effects,traditional properties,different compatibility,and processing methods,which can provide a reference for scientific quality evaluation of Flos Lonicerae Confusae.
Keywords:Flos Lonicerae Confusae  Chemical components  Pharmacological effects  Quality marker
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