妊高征孕妇胎盘微循环功能与脐动脉血流的相关性研究

胎盘微循环功能的监测是产科医生进行临床决策的重要参考内容，它与胎儿胎盘循环直接相关，关系到产科质量的优劣和围产儿的预后。过去常通过查尿雌三醇、尿雌激素／肌酐比值（ｅｓｔｒｉｏｌ／ｃｒｅａｔｉｎｉｎｅ，Ｅ／Ｃ值）等间接监测胎盘微循环功能。目前应用超声多普勒测定脐动脉血流阻力已成为产科监护较理想的手段之一［１，２］，故我们选用超声多普勒测定妊高征孕妇脐动脉血流速度波型收缩期峰值／舒张末期峰值（ｓｙｓｔｏｌｉｃｐｅｒｉｏｄｃｒｅｓｔｖａｌｕｅ／ｄｉｓｔｏｌｉｃｅｎｄｐｅｒｉｏｄｃｒｅｓｔｖａｌｕｅ，…

Study on Placental Microcirculation Function in Pregnancy lnduced Hypertension and Its Relationship with Umbilical Artery Blood Flow

Objective: To study the relationship between placental microcirculation function and umbilical blood flow in pregnancy induced hypertension(PIH) women. Methods: Blood flow velocity S/D and volumetric flow of umbilical artery were detected by Doppler ultrasound in 67 PIH women. Sametimes, their urinary E/C was detected. Results: Placental microcirculation function, whose umbilical artery S/D≥3 gradually reduced for their urinary E/C<15 and their low volumetric flow of umbilical artery. The prevalences of IUGR and 1 min Apgar score were significantly higher in women with S/D≥3 as compared normal umbilical artery blood flow velocity women(S/D<3). Conclusion: The changes of placental microcirculation was related to umbilical artery S/D and volumetric flow. S/D of umbilical artery is a sensitive monitoring index on reaction placental microcirculation function. It can be used to judge pregnancy outcome of PIH women.