| 新型钙通道拮抗剂马尼地平 |
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| 引用本文： | 黄震华. 新型钙通道拮抗剂马尼地平[J]. 中国新药与临床杂志, 2003, 22(4): 241-244 |
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| 作者姓名： | 黄震华 |
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| 作者单位： | 上海第二医科大学附属第九人民医院,心血管病研究室,上海,200011 |
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| 摘 要： | 马尼地平是一种新型的钙通道拮抗剂 ,具有无负性肌力作用、不加快心率、额外的排钠利尿作用、保护肾功能、增加胰岛素敏感性等优点 ,降压作用显著 ,每日 1次服药有很好的降压谷 /峰比值 ,适合高血压的长期治疗
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| 关 键 词： | 钙通道阻滞药 高血压 二氢吡啶类 心率 利尿 马尼地平 |
| 文章编号： | 1007-7669(2003)04-0241-04 |
A new calcium channel antagonist: manidipine |
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| HUANG Zhen hua. A new calcium channel antagonist: manidipine[J]. Chinese Journal of New Drugs and Clinical Remedies, 2003, 22(4): 241-244 |
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| Authors: | HUANG Zhen hua |
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| Abstract: | Manidipine is a new calcium channel antagonist. It has no negative inotropic effect. It does not fast heart rate. It also has the advantage of additional natriuretic effect, renoprotection and increasing of insulin sensitivity. The drug can decrease blood pressure significantly. It has the good antihypertensive trough/peak ratio when used orally once daily. The drug is suitable for the long-term treatment of hypertension. |
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| Keywords: | calcium channel blockers hypertension dihydropyridines heart rate diuresis manidipine |
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