制萎扶胃浓缩丸对小鼠胃肠动力的影响及急性毒性研究 |
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引用本文: | 李喜香,舒劲,任远,李生财,吴国泰,洪秋菊. 制萎扶胃浓缩丸对小鼠胃肠动力的影响及急性毒性研究[J]. 实用中医药杂志, 2011, 27(3): 150-151 |
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作者姓名: | 李喜香 舒劲 任远 李生财 吴国泰 洪秋菊 |
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作者单位: | 1. 甘肃省中医院药剂科,兰州,730070 2. 甘肃中医学院,兰州,730000 |
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基金项目: | 甘肃省卫生厅重点中医药科研项目 |
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摘 要: | 目的:研究制萎扶胃浓缩丸对小鼠胃肠动力的影响及急性毒性。方法:通过测定小鼠胃排空率和肠推进率研究制萎扶胃浓缩丸对小鼠胃肠动力的影响,采用测定LD50评价制萎扶胃浓缩丸急性毒性。结果:制萎扶胃浓缩丸对小鼠胃排空有一定的促进作用(P<0.01),对正常小鼠肠推进未见明显影响,制萎扶胃浓缩丸未见明显急性毒性反应。结论:制萎扶胃浓缩丸对小鼠胃肠动力具有促进作用,口服安全性较高。
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关 键 词: | 制萎扶胃浓缩丸 小鼠 胃排空 肠推进 毒性 研究 |
Effect of Zhiwei Fuwei Concentrated Pill on Gastrointestinal Motility of Mice and Acute Toxicity Study |
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Affiliation: | Li Xixiang,Shu Jin,Ren Yuan et.al |
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Abstract: | Objective:To study the effect of Zhi-wei-fu-wei concentrated pill(ZWFWCP) for gastrointestinal motility and experiment of acute toxicity in mice.Methods:To investigate this effect by testing the gastric emptying rate and intestinal propulsion rate,to determine ZWFWCP acute toxicity by LD50.Result:ZWFWCP can inhibit the gastric emptying in mice(P0.01).It had no effect the intestinal propulsion and acute toxicity in mice.Conclusion:ZWFWCP can promote the gastrointestinal motility,and had better security by orally. |
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Keywords: | the volatile oil angelica sinensis mice gastric empty intestinal propulsion toxicity investigation |
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