穴位注射配合强的松治疗肾病综合征临床疗效观察及对免疫功能的影响

目的:寻找提高治疗肾病综合征临床疗效的最佳方法,并探讨其作用机理.方法:41例患者随机分为2组:治疗组22例采用中药穴位注射配合强的松治疗,对照组19例单纯采用强的松治疗,观察治疗结果并进行比较.结果:治疗组完全缓解率45.5%、总有效率86.4%,分别明显高于对照组的31.6%和63.2%,两组总有效率比较差异有显著性意义(P＜0.05);同时治疗组具有降低高脂血症、提高血浆蛋白及调节免疫功能的作用.结论:中药穴位注射配合强的松治疗肾病综合征能明显提高疗效并增强自身免疫功能.

Observation on clinical therapeutic effect of acupoint-injection therapy combined with prednisone on nephrotic syndrome and effect on immunologic function

Objective To search for the best method for increasing clinical therapeutic effect on nephrotic syndrome. Methods Forty-one cases were randomly divided into 2 groups. The treatment group (n=22) were treated with acupoint-injection of Chinese medicine combined with prednisone, and the control group (n=19) with prednisone. Their therapeutic results were observed and compared. Results The complete remission rate of 45.5% and the total effective rate of 86.4% in the treatment group were significantly higher than 31.6% and 63.2% in the control group, with a significant difference between the two groups in the total effective rate (P<0.05); in the treatment group, blood lipids decreased, plasma proteins raised and immunologic function improved. Conclusion Acupoint-injection of Chinese medicine combined with prednisone can significantly increase therapeutic effect on nephrotic syndrome and strengthen immunologic function.