血液灌流联合血液透析治疗尿毒症并发症46例疗效观察

目的观察血液灌流联合血液透析对尿毒症并发症的疗效。方法将91例维持性透析尿毒症患者分为对照组和观察组,对照组行常规血液透析治疗;观察组行血液灌流联合血液透析治疗。4次治疗后,观察两组患者治疗前后的实验室检测指标变化和并发症状改善情况。结果观察组治疗后甲状旁腺激素、β2微球蛋白、血红蛋白水平改善明显优于对照组（P〈0.05）;观察组难治性高血压、皮肤瘙痒、食欲不振和不宁腿的改善较对照组更为明显（P〈0.05）。结论血液灌流联合血液透析对难治性高血压、皮肤瘙痒、食欲不振和不宁腿等尿毒症并发症有较好的疗效,值得临床推广。

Efficacy of hemoperfusion combined with hemodialysis in treatment of 46 cases of uremia complications

Objective To observe the efficacy of hemoperfusion combined with hemodialysis in treatment of uremia complications. Methods Ninety-one patients with uremia of maintenance herrlodialysis were selected and divided into two groups, the control group and the observation group. The control group was given conventional hemodialysis treat- ment, and the observation group was given hemoperfusion combined with hemodialysis treatment. After treatment of 4 times, the examination indexes change of the laboratory and improvement condition of complications before and after treatment in two groups were observed. Results Parathyroid hormone, ~2-microglobulin and hemoglobin levels of ob- servation group improved more significantly than that of control group （P 〈 0.05）. The improvement of resistant hyper- tension, pruritus, anorexia and restless leg of the observation group was more evident than that of control group （P 〈 0.05）. Conclusion The treatment of hemoperfusion combined with hemodialysis has better efficacy in treatment of ure- mia complications including resistant hypertension, pruritus, anorexia and restless leg, which is worthy to be applied widely in clinical practice.