Endometrial polyps affect uterine receptivity |
| |
| Authors: | Rackow Beth W Jorgensen Elisa Taylor Hugh S |
| |
| Affiliation: | Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut |
| |
| Abstract: | This case-control study evaluated the effect of hysteroscopically identified endometrial polyps on endometrium by means of HOXA10 and HOXA11, known molecular markers of endometrial receptivity. Uteri with endometrial polyps demonstrated a marked decrease in HOXA10 and HOXA11 messenger RNA levels, which may impair implantation. These findings suggest a molecular mechanism to support the clinical findings of diminished pregnancy rates in women with endometrial polyps. |
| |
| Keywords: | Endometrial polyps endometrial receptivity HOX genes infertility |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
