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Lipocalin-1: a potential marker for noninvasive aneuploidy screening |
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| Authors: | McReynolds Susanna Vanderlinden Lauren Stevens John Hansen Kirk Schoolcraft William B Katz-Jaffe Mandy G |
| Affiliation: | a National Foundation for Fertility Research, Lone Tree, Colorado b Biochemistry and Molecular Genetics, University of Colorado, Denver, Colorado c Colorado Center for Reproductive Medicine, Lone Tree, Colorado |
| Abstract: | This study has identified the first protein, lipocalin-1, in the secretome of human blastocysts that is associated with chromosome aneuploidy. The development of a noninvasive technique to determine an embryo's developmental competence, including chromosomal constitution, by analysis of spent IVF culture medium will be a powerful tool for embryo selection in assisted reproductive technologies. |
| Keywords: | Blastocyst secretome noninvasive aneuploidy screening |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |