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In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates
Authors:Zelinski Mary B  Murphy Mark K  Lawson Maralee S  Jurisicova Andrea  Pau K Y Francis  Toscano Natalia P  Jacob Darla S  Fanton John K  Casper Robert F  Dertinger Stephen D  Tilly Jonathan L
Affiliation:a Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Sciences University, Beaverton, Oregon
b Battelle Pacific Northwest Division, Richland, Washington
c Departments of Obstetrics and Gynecology, and Physiology, University of Toronto, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
d Division of Animal Sciences, Oregon National Primate Research Center, Oregon Health and Sciences University, Beaverton, Oregon
e Litron Laboratories, Rochester, New York
f Vincent Center for Reproductive Biology, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
Abstract:
Keywords:Fertility preservation   cancer   ovary   oocyte   monkey   human   sphingosine-1-phosphate   FTY720
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