Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice. |
| |
| Authors: | V Del Gobbo, N Villani, S Marini, E Balestra, R Cali |
| |
| Affiliation: | Department of Experimental Medicine, II University of Rome, Italy. |
| |
| Abstract: | PR8 virus depressed interleukin-2 (IL-2) and natural killer (NK) cell activity in BALB/c infected mice. IL-2 production was not dependent on (i) a decreased number of T cells or (ii) a primary defect in IL-1 production, but on a T-suppressor cell subpopulation. In fact, when T suppressor cells were removed from infected spleen cells, we observed normal levels of IL-2 activity. |
| |
| Keywords: | |
|
|
