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Granulatimide and 6-bromogranulatimide, minor alkaloids of the Brazilian ascidian Didemnum granulatum.
Authors:R Britton  J H de Oliveira  R J Andersen  R G Berlinck
Institution:Instituto de Química de S?o Carlos, Universidade de S?o Paulo, CP 780, CEP 13560-970, S?o Carlos, SP, Brazil.
Abstract:Reinvestigation of the extract of the ascidian Didemnum granulatum collected on the Brazilian coastline led to the isolation of two minor compounds, granulatimide (2) and 6-bromogranulatimide (3), which have been identified by analysis of their spectroscopic data. The isolation of 2 and 3 from D. granulatum corroborates previous assumptions about the occurrence of granulatimide as a natural product.
Keywords:
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