Kojewnikow综合征12例报告

目的 研究Kojenikow综合征的病因、临床特征、脑电图及影像学改变。方法 对12例Kojenikow综合征患者进行临床、脑电图及影像学观察。结果 Kojenikow综合征有局限性持续性肌肉抽搐和单纯部分运动性癫痫持续发作2个基本特征，病因以病毒性脑炎最多见，其他为脑膜脑炎、脑质瘤、脑囊虫病、脑梗死、糖尿病及隐源性癫痫。并发现其病灶分布以分水岭区为多见。结论 Kojenikow综合征分2型，综合分析临床、脑电图及影像学检查结果，有助于提高本病的诊断率并发现病因。大部分患者抗癫痫治疗效果较差，预后不良。

Kojewnikow syndrome 12 cases report

Objective To investigate causes for Kojewnikow syndrome,by observing its clinical characteristics,electroencephalography and findings in imaging scanning. Methods Twelve patients with Kojewnikow syndrome were accessed with clinical observation, electroencephalography and imaging scanning. Results Kojewnikow syndrome is clinically charaterized by secouse twitching and simple partialis motor continua.Viral encephalitis is by far the most of common cause for Kojewnikow syndrome, followed by meningo-encephalitis,cerebral glioma,cerebral cysticercosis, cerebral infarction, diabetes, and cryptogenic epilepsyKojewnikow syndrome tends to occur in watershed area. Conclusions Kojewnikow syndrome falls into two main groups.It is important to improve the diagnosis and find the causes for Kojewnikow and to access its clinical manifestations, electroencephalography and findings in the imaging scanning.The seizures cannot be readily controlled by the anticonvulsants,so the prognosis is poor.