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拉米夫定联合胸腺肽α1治疗重型乙型肝炎的临床研究
引用本文:王堂明,李玉龙,邱波,李树民,王云,张雪梅,邹荣. 拉米夫定联合胸腺肽α1治疗重型乙型肝炎的临床研究[J]. 国际流行病学传染病学杂志, 2007, 34(3): 156-158
作者姓名:王堂明  李玉龙  邱波  李树民  王云  张雪梅  邹荣
作者单位:617061,四川省攀枝花市第四人民医院(传染病医院)肝病治疗中心
基金项目:攀枝花市科学技术局科研资助项目(2004~2006)
摘    要:目的观察拉米夫定(LAM)联合胸腺肽α1治疗重型乙型肝炎的疗效。方法选择重型乙型肝炎患者88例,治疗组44例用LAM联合胸腺肽α1治疗,对照组44例不作任何抗病毒及免疫调节治疗,两组均常规使用护肝、对症治疗。结果治疗组与对照组比较,生存率经统计学处理有显著差异(P<0.01)。结论LAM联合胸腺肽α1治疗重型乙型肝炎可明显降低患者死亡率,提高生存率,值得临床进一步研究。

关 键 词:拉米夫定  胸腺肽α_1  乙型肝炎  死亡率

Effect of lamivudine combined with thymosin-alpha 1 in the treatment of patients with severe hepatitis B
WANG Tang-ming,LI Yu-long,QIU Bo,LI Shu-min,WANG Yun,ZHANG Xue-mei,ZOU Rong. Effect of lamivudine combined with thymosin-alpha 1 in the treatment of patients with severe hepatitis B[J]. International Journal of Epidemiology and Infectious Disease, 2007, 34(3): 156-158
Authors:WANG Tang-ming  LI Yu-long  QIU Bo  LI Shu-min  WANG Yun  ZHANG Xue-mei  ZOU Rong
Abstract:Objective To explore the effect of lamivudine combined with thymosin-alpha 1 in the treatment of patients with severe hepatitis B. Method 88 cases patients with severe hepatitis B were selected, 44 patients in treatment group were received lamivudine combined with thymosin-alpha1, 44 patients in control group were received no antiviral treatment or immunity regulate. 2 groups were received ordinary synthetic treatment. Results Compared the treatment group with the control group, the survival rate had significantly difference(P<0.01). Conclusions Lamivudine combined with thymosin-alpha 1 in the treatment of patients with severe hepatitis B can effectively decrease the mortality and increase the survival rate of the patients. It is worth doing more systematic clinic study.
Keywords:Lamivudine  Thymosin-alpha1  Hepatitis B  Mortality
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