| 沙棘油乳抗大鼠慢性萎缩性胃炎和胃溃疡作用研究 |
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| 引用本文： | 黄彦丽,解娟,杨凌云.沙棘油乳抗大鼠慢性萎缩性胃炎和胃溃疡作用研究[J].中国药房,2002,13(10):590-591. |
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| 作者姓名： | 黄彦丽 解娟 杨凌云 |
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| 作者单位： | 陕西省人民医院药剂科,西安市,710068 |
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| 摘 要： | 目的 :研究沙棘油乳抗大鼠慢性萎缩性胃炎和胃溃疡作用。方法 :采用动物的萎缩性胃炎、胃溃疡模型 ,评价沙棘油乳的抗萎缩性胃炎、胃溃疡作用。结果 :沙棘油乳能明显防止脱氧胆酸钠和应激所致慢性萎缩性胃炎、胃溃疡 ;对大鼠幽门结扎引起的急性胃溃疡指数有显著降低作用 ;对小鼠消炎痛 -乙醇性溃疡有显著对抗作用。结论 :沙棘油乳具有制酸、保护胃粘膜的作用
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| 关 键 词： | 沙棘油乳 胃溃疡 慢性萎缩性胃炎 |
| 文章编号： | 1001-0408(2002)10-0590-02 |
| 修稿时间： | 2002年3月12日 |
Study on the Actions of Seabuckthorn Oil Emulsion Against Chronic Atrophic Gastritis and Gastric Ulcer in Rats |
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| HUANG Yanli,XIE Juan,YANG Lingyun.Study on the Actions of Seabuckthorn Oil Emulsion Against Chronic Atrophic Gastritis and Gastric Ulcer in Rats[J].China Pharmacy,2002,13(10):590-591. |
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| Authors: | HUANG Yanli XIE Juan YANG Lingyun |
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| Abstract: | OBJECTIVE:To study the actions of seabuckthorn oil emulsion against chronic atrophic gastritis and gastic ulcer in rats.METHODS:Chronic atrophic gastritis and gastric ulcer models were established in rats and mice and the antiulcer and anti-chronic atrophic gastritis actions of seabuckthorn oil emulsion were determined.RESULTS:Seabuckthorn oil emulsion could obviously prevent gastric ulcer and chronic atrophic gastritis induced by deoxycholic acid and stress and could decrease the index of acute gastric ulcer caused by ligature of pylorus in rats and could oppose the ulcer induced by indomethacin-ethanol significantly in mice.CONCLUSION:The results suggest that the antiulcer and anti-chronic atrophic gastritis actions of seabuckthorn oil emulsion may be related with its protection of the gastric mucosal barrier and neutralization of acid. |
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| Keywords: | seabuckthorn oil emulsion gastric ulcer chronic atrophic gastritis |
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