Behavior outbursts, orofacial dyskinesias, and CSF pleocytosis in a healthy child |
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Authors: | Tamma Pranita D Agwu Allison L Hartman Adam L |
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Institution: | Department of Pediatric Infectious Diseases, Johns Hopkins Medical Institution, 200 N Wolfe St, Suite 3150, Baltimore, MD 21287, USA. ptamma1@jhmi.edu |
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Abstract: | Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis represents a new category of immune-mediated neurologic disorders. Viral encephalitis is often the presumptive diagnosis because of the acute neurologic changes, cerebrospinal fluid lymphocytic pleocytosis, and occasional hyperthermia. We report here the case of a previously healthy 7-year-old boy with new-onset aggressive behavior, seizure activity, and orofacial dyskinesias with cerebrospinal fluid and serum that tested positive for anti-NMDA receptors. |
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