艾滋病合并肺癌、肺结核合并肺癌与单纯肺癌的病理特征及肺内占位CT特征的比较

目的  分析艾滋病合并肺癌、肺结核合并肺癌与单纯肺癌的病理特征及肺内占位CT特征。方法  选择2021年11月~2022年6月我院收治的36例艾滋病合并肺癌、36例肺结核合并肺癌及36例单纯肺癌患者为研究对象, 收集其一般资料、临床症状、病理特征、肺内占位CT特征等临床资料, 并将3组患者上述资料进行对比分析。结果  艾滋病合并肺癌组、肺结核合并肺癌组发热、纳差比例均高于单纯肺癌组(P < 0.05), 艾滋病合并肺癌组贫血、真菌感染比例高于肺结核合并肺癌、单纯肺癌组(P < 0.05), 3组其他临床症状差异无统计学意义(P>0.05)。艾滋病合并肺癌组腺癌比例高于肺结核合并肺癌组、单纯肺癌组(P < 0.05), 鳞癌比例低于肺结核合并肺癌组、单纯肺癌组(P < 0.05), 肺结核合并肺癌组病理分型与单纯肺癌组的差异均无统计学意义(P>0.05), 3组TNM分期差异均无统计学意义(P>0.05)。艾滋病合并肺癌组肺内占位CT表现中纤维条索影比例均高于肺结核合并肺癌组和单纯肺癌组(P < 0.05);肺结核合并肺癌患者肺内占位CT表现中长毛刺征、空洞、纵膈淋巴结增大、胸腔积液均高于单纯肺癌组(P < 0.05), 粟粒性阴影、卫星灶比例高于艾滋病合并肺癌组和单纯肺癌组(P < 0.05)。结论  艾滋病合并肺癌、肺结核合并肺癌与单纯肺癌的病理特征及肺内占位CT特征存在不同之处, 临床可结合患者病理特征及肺内占位CT特征对不同类型肺癌患者病情予以评估。

Comparation of pathological features and CT features of pulmonary space occupying in AIDS patients with lung cancer,tuberculosis patients with lung cancer and simple lung cancer

  Objective  To compare the pathological features and CT features of pulmonary space occupying in AIDS complicated with lung cancer, tuberculosis complicated with lung cancer and simple lung cancer.  Methods  Thirty-six patients with AIDS combined with lung cancer, 36 patients with tuberculosis combined with lung cancer and 36 patients with simple lung cancer admitted to our hospital from November 2021 to June 2022 were selected as the research objects.General data, clinical symptoms, pathological characteristics, and CT features of lung space occupying lesions were collected, and the above data of the three groups of patients were compared.  Results  The proportions of fever and poor appetite in the AIDS combined lung cancer group and the tuberculosis combined lung cancer group were higher than those in the simple lung cancer group (P < 0.05).The proportion of anemia and fungal infection in the group of AIDS with lung cancer was higher than that in the group of tuberculosis with lung cancer and the group of simple lung cancer (P < 0.05).There was no significant difference in other clinical symptoms among the three groups (P>0.05).The proportion of adenocarcinoma in the AIDS combined lung cancer group was higher than that in the tuberculosis combined lung cancer group and the simple lung cancer group (P < 0.05).The proportion of squamous cell carcinoma was lower than that in the tuberculosis combined lung cancer group and the simple lung cancer group (P < 0.05).There were no significant difference in pulmonary pathological classification between the tuberculosis combined lung cancer group and the simple lung cancer group (P>0.05).There were no significant difference in TNM staging among the three groups (P>0.05).The proportion of fibrous shadow in CT manifestations of HIV/AIDS patients with lung cancer was higher than that in pulmonary tuberculosis patients with lung cancer and lung cancer alone (P < 0.05).The CT findings of pulmonary space occupying in patients with pulmonary tuberculosis combined with lung cancer were higher than those in patients with simple lung cancer (P < 0.05).The percentages of miliary shadow and satellite focus were higher than those in patients with AIDS combined with lung cancer and patients with simple lung cancer (P < 0.05).  Conclusion  There are differences in pathological features and CT features of pulmonary space occupying between AIDS combined with lung cancer, tuberculosis combined with lung cancer and simple lung cancer.Clinical evaluation of patients with different types of lung cancer can be made according to the pathological features and CT features of pulmonary space occupying.