临床药师参与1例胰岛素制剂过敏糖尿病患者的降糖方案制定

摘 要 目的： 分析1例胰岛素制剂致过敏的具体病例，探讨临床药师在参与治疗胰岛素制剂过敏的糖尿病患者中的作用。方法: 1例糖尿病患者使用胰岛素治疗过程中出现过敏，多次换用不同种类胰岛素但过敏症状未明显好转，临床药师建议停用含鱼精蛋白的胰岛素，改用甘精胰岛素联合既往口服降糖药物治疗。结果: 调整为临床药师建议的降糖治疗方案后，患者住院期间过敏症状较前明显好转，之后未再次出现过敏症状，最终达到满意的降糖治疗效果。结论:临床药师参与患者对胰岛素制剂过敏的治疗，可运用药学知识，准确的判断过敏原，制定个体化的降糖治疗方案，对提高临床诊疗水平及保障患者用药安全性具有帮助和促进作用。

Participation of Clinical Pharmacist in Hypoglycemic Program for One Case of Diabetes Allergic to Insulin Preparations

ABSTRACT Objective: To analyze one case of diabetes allergic to insulin preparations and investigate the role of clinical pharmacist in the treatment. Methods: Different insulin preparations were tried out after the patient was allergic to one kind of insulin preparation. However, the allergic symptoms were not improved significantly. Clinical pharmacist recommended to use glargine combined with oral hypoglycemic drugs instead of insulin containing protamine for the patient. Results:The allergic symptoms of the patient were improved significantly after the drug adjustment in the hypoglycemic program by clinical pharmacist. The blood glucose was controlled and allergic symptoms didn't show again during the hospitalization. Conclusion:Clinical pharmacist can participate in the treatment of diabetes allergic to insulin preparations through identifying allergens accurately and improving individual hypoglycemic program using pharmacological knowledge. It is important to improve the clinical diagnosis and treatment, and ensure and promote the safety of medical treatment and drug use.