环磷腺苷葡胺与美托洛尔联合治疗心力衰竭临床观察

目的 研究环磷腺苷葡胺（心先安）与美托洛尔联合应用对心力衰竭的临床疗效.方法 对50例确诊的心力衰竭患者随机分为A组（治疗组）26例和B组（对照组）24例,对照组给予常规基础治疗,治疗组为在对照组的基础上加用心先安和美托洛尔,观察两组治疗3周后临床疗效及心功能的变化.两组治疗前后均作超声心动图,测定左心室射血分数、左心室舒张末容积、左心室收缩末容积.结果 心先安联合美托洛尔治疗在对心力衰竭的临床疗效及心功能的改善方面均优于对照组.结论 心先安与美托洛尔联合应用对心力衰竭有较好的疗效.

Clinical evaluate of meglumine adenosine cyclophosphate and metoprolol in the treatment of chronic heart failure

Objective To evaluate the clinical effect of a combination application of meglumine adenosine cyclophosphate and metoprolol in chronic heart failure.Methods Put 50 patients divided into two group randomly:group A(treated group) which has 26 cases and group B(control group) which has 24 cases.Patients of group B will receive a basal treatment in a routine way while patients of group A will receive a basal treatment as well as a additional treatment of meglumine adenosine cyclophosphate and Metoprolol.The clinical effect and changes of heart function will be evaluated in the two group with different treatment after three weeks,left ventricular ejection fraction and left nentricular volume at end-diastole,left nentricular volume at end-systolic were measured by M-mode.Echocardiography before and after curative in two group.Results Patients in the group with a combination application of meglumine adenosine cyclophosphate and metoprolol has a better clinical effect and a improved heart function than the control group.Conclusion A combination application of meglumine adenosine cyclophosphate and metoprolol has good curative effect in treating heart failure.