阴茎疣状癌的临床诊断和治疗

目的为了探讨阴茎癌的少见类型疣状癌的临床诊断和治疗。方法回顾性分析1999年12月至2009年12月10例阴茎疣状癌的临床资料,结合文献复习进行讨论。结果 10例患者均经行阴茎部分切除术,其中1例在当地医院行包皮环切,术后3个月发现阴茎结节,活检确诊为阴茎疣状癌,再行阴茎部分切除术,1例误诊为乳头状瘤,1例经反复复发切除3次后确诊。所有患者均未行腹股沟淋巴结清除及放化疗。患者随访0.7～9年,1例患者自然死亡,其余患者均未见肿瘤复发或转移。结论阴茎疣状癌细胞分化良好,以局部侵袭性生长为主,恰当的手术切除效果肯定,术后不需辅助性放化疗,但应严密观察局部复发。

Diagnosis and treatment of penile verrucous carcinoma

Objective Penile verrucous carcinoma is a rare disease, the experience in diagnosis and treatment of the disease was presented in this paper.Methods The clinical and pathological data of 10 patients with penile verrucous carcinoma were analyzed with literature review. Results： All the tumors showed exophytic papillary lesions, ranged from 0.4 to 4 cm in diameter. All ten patients received partial penectomy and the surgical margins were negative. None of 10 patients received ilioinguinal lymphadenectomy. All cases were regularly followed up from 0.7 to 9 years,without have recurrence, only one patient died from other reseaon.Conclusion Verrucous carcinoma of the penis is a well differential disease with low malignant potential and locally aggressive nature. Misdiagnosis may occur due to incorrect biopsy. Favorable outcomes can be achived by surgery without any adjuvant therapy, but patients should be carefully followed up.