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Binding of3H-diazepam in rat brain eleven months after termination of corazole kindling
Authors:M N Karpova  V V Zhulin  R N Glebov  O Yu Pankov  R I Kruglikov
Institution:(1) Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow;(2) Institute of Higher Nervous Activity, Russian Academy of Sciences, Moscow
Abstract:Binding of3H-diazepam in rat cerebellum decreases by 14% (p<0.05) 11 months after termination of kindling and one day after injection of a test dose of corazole (30 mg/kg), while it increases by 19.5% after a single injection of a convulsive dose of corazole (50–75 mg/kg). No changes are found in the cortex. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N o 2, pp. 135–137, February, 1994 Presented by G. N. Kryzhanovskii, Member of the Russian Academy of Medical Sciences
Keywords:cerebellum                      brain cortex                      corazole kindling  diazepam                      benzodiazepine receptors
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