Binding of3H-diazepam in rat brain eleven months after termination of corazole kindling |
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Authors: | M N Karpova V V Zhulin R N Glebov O Yu Pankov R I Kruglikov |
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Institution: | (1) Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow;(2) Institute of Higher Nervous Activity, Russian Academy of Sciences, Moscow |
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Abstract: | Binding of3H-diazepam in rat cerebellum decreases by 14% (p<0.05) 11 months after termination of kindling and one day after injection of a test dose of corazole (30 mg/kg), while it
increases by 19.5% after a single injection of a convulsive dose of corazole (50–75 mg/kg). No changes are found in the cortex.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N
o
2, pp. 135–137, February, 1994
Presented by G. N. Kryzhanovskii, Member of the Russian Academy of Medical Sciences |
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Keywords: | cerebellum brain cortex corazole kindling diazepam benzodiazepine receptors |
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